Further studies on the abnormal factor X (factor X Friuli) coagulation disorder: a report of another family.

Another patient with a congenital coagu-lation disorder due to the presence of an abnormal factor X (factor X Friuli) is presented. The proposita was a 43-yr-old white female who had a bleeding tendency from early childhood (epistaxes, monorrhagias, bleeding after tooth extractions and other surgical procedures, posttraumatic hemarthroses, bleeding from the gums and postpartum hemorrhages). The coagulation work-up demonstrated a prolonged prothrombin time, prolonged partial thromboplastin time, abnormal prothrombin consumption , and abnormal thromboplastin generation corrected by normal serum. tests and fibrinolysis were normal. Mr.